Sandvik Materials Technology return to home page
For Today's Orthopaedic Professional
visits:  this month all time total site hits
  5,383 536,682 44,382,042

Zimmer Host 4th Interactions In Hip And Knee Arthroplasty
Authors: Andy Sutcliffe, Marketing Director Zimmer UK and
Jeremy Martindale, Director Surgical Skills Unit, Dundee

Anterior Lumbar Interbody Fusion Using Stand Alone Lumbar Interbody Fusion Device (Stalif ™)
Author: S Tafazal, P Sell, University Hospitals of Leicester, UK

BOA 2005





Zimmer Host 4th Interactions In Hip And Knee Arthroplasty
Authors: Andy Sutcliffe, Marketing Director Zimmer UK and
Jeremy Martindale, Director Surgical Skills Unit, Dundee

Once again Zimmer built on the success of the previous Interactions format to host the 4th Interactions in Arthroplasty meeting at the Grove hotel, Hertfordshire on May 16th and 17th 2005. Professor David Barrett (Southampton) hosted the Knee meeting with Professor Kelly Vince (Los Angeles) and Dr Michael Kelly (New York) together with Mr Rob Middleton (Bournemouth) hosting the Hip meeting with Mr Paul Roberts (Newport) and Professor Aaron Rosenberg (Chicago).

Further faculty included Jean-Noel Argenson (Marseille), Lars Carlsson (Gothenberg), Evan Williams (Capetown) Heinz Rottinger (Munich), Roy Crowninshield (Warsaw) and Claude Rieker (Winterthur). This ensured an overall delegate/faculty ratio of 4.6 to help facilitate this extensive course.

The main purpose of this meeting was to allow all those attending to explore current issues in the provision of high quality primary lower limb joint replacement. This year’s meeting was devoted to contemporary arthroplasty of the hip and knee, including resurfacing of the hip, MIS and unicondylar arthroplasty of the knee. The concept of minimal invasive surgery was widely debated, and consensus reached as to the appropriate application of these new techniques. Additional sessions covered advances in biomaterials, alternative treatment options for the younger patient, and the philosophical considerations of the need for progress, tempered with caution.

As always the meeting contained a high level of interactive debate and discussion utilising electronic voting systems and break out groups to ensure feedback from over 120 Orthopaedic surgeons in attendance. The feedback from delegates was very positive, with all of the sessions being rated good or excellent.

One delegate described the Knee meeting as: “Impressive national and international faculty giving authoritative opinion and instruction on common problems with knee arthroplasty”. Others noted how the interactive format was a refreshing change, while the course was was both professional and well organised.

Questions were posed to the audience about the surgical techniques and approaches they have preferences for, with the key results listed below.

Knee

  • 72% of the audience expressed the fact that they had actively been trying to reduce the size of the incision used for total or unicondylar knee arthroplasty.
  • 36% of the audience had adopted an MIS approach for unicondylar knee replacement; 28% felt that they were still learning the technique, and a further 32% had never tried the procedure.
  • 59% had not tried MIS Mini total knee.
  • The single biggest cause of failure, other than that due to infection, was felt to be polyethylene wear by 37%, and failure of the bone prosthesis interface by the remaining 63%.
Hip
  • The audience identified their priority in THR as longevity of the implant (66%), ultimate functional level (29%), and lowest rate of failure (5%). Nobody felt that rapid recovery was the most important consideration.
  • 59% preferred the lateral Hardinge approach to the posterior. 45% routinely perform hip replacement through a short incision, with only 9% utilising a special approach to facilitate minimally invasive surgery.
  • An overwhelming majority, of 98%, preferred resurfacing to total joint replacement for the younger patient, with 51% regarding the blood supply to the resurfaced femoral head to be a critical issue.
  • 78% of the audience would prefer to have their own hip resurfaced, rather than replaced.
Zimmer intend to take the meeting to a new level in 2006 with the 5th Interactions™ meeting being planned for May 2006, and will address controversies in revision arthroplasty of the hip and knee. The Zimmer Interactions in Trauma™ Meeting will be also be held in Leicester on Thursday 3rd November 2005, and will consider the management of complex trauma to the tibia. Spinal should also benefit with its own Interactions format planned for 2006.

Zimmer is committed to educational excellence and to the continued improvement in outcomes and patient safety afforded by high quality and innovative medical education with the Zimmer Institute™ offering a variety of courses, tailored to the interests and needs of the individual. These courses aim to promote excellence in surgery, by developing procedures and skills in the individual, and by promoting the principles of team working, multiprofessional care, and lifelong learning and reflective practice.

top  | next
Anterior Lumbar Interbody Fusion Using Stand Alone Lumbar Interbody Fusion Device (Stalif ™)
Author: S Tafazal, P Sell, University Hospitals of Leicester, UK

Introduction
Current controversies in the treatment of severe persistent axial back pain revolve around three main treatment options. That is, functional restoration programs, spinal fusion or flexible motion preserving operations. All three options have reported success rates and careful patient selection is critical to outcome. Complex health economy issues may be the determinants of what treatment is offered to what patient.

The aim of this study was specifically to assess any difference in outcome between post discectomy instability severe axial pain and primary severe axial back pain. Significant loss of disc height is a relative contraindication to disc replacement but not to anterior interbody fusion.

Anterior lumbar interbody fusion has been used for many years to achieve fusion in patients with degenerative disc disease. A variety of different techniques have been described in the literature1-5, with varying success rates. The results of anterior lumbar spinal fusion vary considerably in the literature and there is a lack of reporting standardised outcome measures in the literature.

Although both anterior and posterior approaches for spinal fusion are well described, the choice of procedure is surgeon dependent. Reported results of cohort studies may be related to the enthusiasm of the reporter. A study comparing the approaches7 concluded that anterior interbody fusion with cages, for single level lumbar pathology, is associated with significantly less peri-operative morbidity than posterolateral fusion with pedicle screws. They did not find any significant differences in the clinical outcome between the two approaches.

A study by Greenough et al6 found that anterior fusion resulted in better clinical results based on the LBOS, with 40% of patients having an excellent or good result in the anterior fusion group and only 19% achieving a similar result in the posterolateral fusion group. They concluded that results of instrumented posterolateral fusion are poor. They believe that this is due in part, to damage to the spinal musculature during the posterior approach as well as anterior movement still occurring despite solid posterior fusion.

Anterior lumbar interbody fusion using STALIF™
The STALIF™ (Stand Alone Lumbar Interbody Fusion) device was first developed as a titanium implant that is inserted anteriorly into the disc space after clearance of disc material and is unique in that it is fitted in situ with screws. A recent new development is the use of PEEK-OPTIMA® so that graft evolution can be monitored, overcoming problems of graft extrusion, compression and instability in patients undergoing spinal fusion. The STALIF™ device has been reported to allow interbody fusion to occur, prevents graft extrusion and restores the normal lumbar lordosis and importantly, only requires a single anterior procedure due to its unique screw fixation. The procedure also allows direct removal of the disc material, which may be the main source of pain in patients with degenerative disc disease. Posterior lumbar muscle integrity is preserved.

Consent and planning
In our practice, patients are offered the possibility of fusion surgery if they have complied with extensive spinal muscle reconditioning in the form of physical therapy. Concordance with pain provocation discography is essential in primary axial back pain. In post discectomy axial pain the discography is in part to determine normal morphology above or below the proposed fusion level. Male patients are offered sperm banking as part of the discussion regarding retrograde ejaculation.

Operative technique
There are various operative approaches available. The operation is commonly performed through a Pfannenstial incision for the L5-S1 level and via a muscle splitting, retroperitoneal approach for all other lumbar levels. It really depends upon surgeon’s choice after discussion with the patient about risks and benefits.

A trans-peritoneal approach may have a higher rate of retrograde ejaculation in males, while a retroperitoneal approach may have a higher venous vascular injury rate. Adequate exposure of the disc above, below and laterally must be achieved with suitable retraction. Operative level must be confirmed by X-Ray. After adequate exposure of the disc space, all disc material is excised and the endplates are removed to expose good cancellous bone.

The hard outer cortical rim should be preserved. The STALIF™ device is packed with bone graft or bone substitute and then inserted. All the patients in this reported study had cortico-cancellous bone harvested from the iliac crest.

Clinical results
We have performed a prospective cohort study and looked at patients undergoing anterior lumbar interbody fusion using the STALIF™ device with a minimum 2 year follow-up. Our results show a clinically significant improvement in the Oswestry disability index in 81% of patients. All our patients had already had a minimum 1 year trial of conservative management, which included physiotherapy, regular analgesia and a functional restoration programme in most cases.

The primary diagnosis was back pain due to degenerative disc disease, which was confirmed by pre-operative MRI scanning and all patients had provocative discography to confirm the disc as the source of pain. The patients were followed up for a minimum of 2 years and our primary outcome measures included Oswestry disability index (ODI), low back outcome score (LBOS) and visual analogue score (VAS).

The Mean pre-operative ODI score was 58 and at 2 years follow-up this had decreased to 31 [p=0.004]. Similarly the mean LBOS was 21 pre-operatively and increased to 41 [p=0.005] at 2 years follow-up. The Mean VAS score for back pain was 83mm pre-operatively and this had decreased to 49mm at 2 years follow-up [p=0.01]

When the data was analysed according to the pre-operative pathology we found that patients who had back pain post-discectomy showed a greater improvement in their ODI compared to patients who had back pain alone. The mean change in ODI for the back pain group was 17 points whereas the change in ODI for the back pain post-discectomy group was 29 points [p=0.33].

We found that although plain radiographs give some information about the position of the implant, it is very difficult to assess fusion on radiographs in all the patients, as the titanium device used prior to the introduction of PEEK-OPTIMA® does not allow accurate assessment on plain radiographs. We found no cases of loose screws or subsidence of the implant at 2 years follow-up.

The main complication in our group of patients was common iliac vein tear, which occurred in 2 patients. This was recognised and repaired intra-operatively with no untoward effects. One of our patients developed retrograde ejaculation post-operatively, which settled spontaneously after 24 months.


We believe that patient selection is probably one of the factors determining a good outcome. All our patients had already had a period of conservative treatment, including physiotherapy, regular analgesia and a functional restoration programme. A randomised study has previously indicated that cognitive intervention and exercises in patients with chronic low back pain and disc degeneration has similar outcomes to patients treated with lumbar fusion8. We therefore believe that fusion should only be considered once a conservative regime has been tried and failed, which has also been suggested by other authors in the literature9.

Challenges
Implant manufacturers and distributors face many challenges in a competitive and changing health care market. Purchasers require evidence to support expenditure. In Britain at present a major threat is the introduction of ‘payment by results’. The NHS tariff means that for the treatment of orthopaedic conditions there is a National maximum price, set to cover hospital costs and implant costs. Currently it appears set at £4,900 for primary lumbar fusion/arthroplasty procedures. Health authority purchasing strategies may therefore have a major impact on implant selection.

The STALIF™ device has been tried and tested for 12 years of clinical practice in the unit reporting these results. The senior author has no commercial interest in the device. He does believe it has an important clinical role as a safe and clinically effective implant that is also cost effective for the modern health service.

Conclusion
We believe that anterior lumbar interbody fusion with the STALIF™ device is a safe and effective treatment for patients with severe axial spinal pain. We were pleased to find that the results in post discetomy pain syndromes were favourable. We believe that patient selection is the most important determinant of outcome. It is useful to have an effective graft support device to assist in achieving the desired treatment goal.

References
  1. Madan S, Boeree N.R: Containment and Stabilisation of Bone Graft in Anterior Lumbar Interbody Fusion: The Role of the Hartshill Horseshoe Cage. J Spinal Disord April 2001 Vol 14(2); 104-108.
  2. Penta M, Fraser R.D: Anterior Lumbar Interbody Fusion: A Minimum 10-year Follow-up. Spine 15 Oct 1997, Vol 22(20); 2429- 2434.
  3. Freebody D, Bendall R, Taylor R.D: Anterior transperitoneal lumbar fusion. J Bone Joint Surg Br 1971, 53:617-627.
  4. Flynn J.C, Hoque M.A: Anterior fusion of the lumbar spine. J Bone Joint Surg Am 1979, 61:1143-1150.
  5. Sasso R.C, Kitchel S.H, Dawson E.G: A prospective, randomised controlled clinical trial of anterior lumbar interbody fusion using a titanium cylindrical threaded fusion device. Spine 15 Jan 2004, Vol 29(2); 113-22.
  6. Greenough C.G, Peterson M.D, Hadlow S, Fraser R.D: Instrumented Posterolateral Lumbar Fusion: Results and Comparison with Anterior Interbody Fusion. Spine February 15 1998, Vol 23(4); 479-486.
  7. Pradhan B.B, Nassar J.A, Delamarter R.B, Wang J.C: Single-Level Lumbar Spine Fusion: A Comparison of Anterior and Posterior Approaches. J Spinal Disord Tech Oct 2002, Vol 15(5); 355-361.
  8. Ivar B.J, Sorenson R.F, Nygaard O, Indahl A et al: Randomised clinical trial of lumbar instrumented fusion and cognitive intervention and exercises in patients with chronic low back pain and disc degeneration. Spine Sep 1 2003, Vol 28(17); 1913-21.
  9. Nachemson A, Zdeblick T.A, O’Brien J.P: Lumbar disc disease with discogenic pain. What surgical treatment is most effective? Spine Aug 1 1996, Vol 21(15); 1835-8.


top  | next
BOA 2005


British Orthopaedic Association
Annual Congress 2005

21-23 September
Birmingham International Convention Centre


This year’s Annual Congress is almost upon us once again, this time it will be returning to the impressive surroundings of the Birmingham International Convention Centre. If you are planning on attending the congress, then make sure you have registered, which can be done by downloading the registration form from www.boa.ac.uk.

Once again, BOA has arranged a social event and, as has become the norm, it is co-sponsored by OPN. The Opening Reception is being held on Wednesday 21st September at Birmingham Museum & Art Gallery in Chamberlain Square, from 6.15pm - 7.15pm. As usual, it is an informal reception, with an informal dress code and will provide an opportunity to wind down and meet in a rather more relaxed atmosphere.

The reception is free to all attending delegates, while guests and exhibitors can pre-order their tickets from Janet Mills on 02392 570888 at a cost of £25.

click here for a floor plan and exhibitor listing.




top of page     readers comments     contact us     webmaster     legal notices     home     subscribe
Current Issue Orthopaedic Products SurgeonSpeak Future Events Articles Company Info OPNews
Copyright 2005 © Pelican Magazines Ltd  -  developed by netdirect sales

a Pelican Group Company